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A human recombinant monoclonal antibody to cocaine: Preparation, characterization and behavioral studies

Synthesis, biological evaluation and docking analysis of 3-methyl-1-phenylchromeno[4,3-c]pyrazol-4(1H)-ones as potential cyclooxygenase-2 (COX-2) inhibitors

Discovery of Cathepsin S Inhibitor LY3000328 for the Treatment of Abdominal Aortic Aneurysm

Discovery of Cathepsin S Inhibitor LY3000328 for the Treatment of Abdominal Aortic Aneurysm

Abstract ImageLY 3000328 Eli Lilly….INNOVATOR (3R,4S)-4-(4-fluorobenzamido)-6-(4-(oxetan-3-yl)piperazin-1-yl methylcarbamate Specific rotation: [α]D25 = 55.19 (c = 10,DMSO).

Cathepsin S (Cat S) plays an important role in many pathological conditions, including abdominal aortic aneurysm (AAA). Inhibition of Cat S may provide a new treatment for AAA. To date, several classes of Cat S inhibitors have been…

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An integrated strategy for the conversion of cellulosic biomass into [gamma]-valerolactone

An integrated strategy for the conversion of cellulosic biomass into [gamma]-valerolactone

Catal. Sci. Technol., 2014, 4,3626-3630
DOI: 10.1039/C4CY00717D, Communication Valerio Molinari, Markus Antonietti, Davide Esposito
A new integrated strategy for the synthesis of GVL from beechwood based on the use of 2-MeTHF and RANEY Ni is presented. Valerio Molinari,a Markus Antoniettia and Davide…

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Mesoporous carbon nitride grafted with n-bromobutane: a high-performance heterogeneous catalyst for the solvent-free cycloaddition of CO2 to propylene carbonate

Catal. Sci. Technol., 2014, Advance Article
DOI: 10.1039/C4CY00770K, Paper Jie Xu, Fei Wu, Quan Jiang, Yong-Xin Li
Mesoporous carbon nitride grafted n-bromobutane shows high catalytic activity in the solvent-free cycloaddition of CO2 with propylene oxide to propylene carbonate, affording a maximum yield of 88% with a TOF up to 10.7 h-1. http://pubs.rsc.org/en/Content/ArticleLanding/2014/CY/C…

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